Talon Runes explained
There's one set of runes for Talon on patch 14.24 that is the clear favorite for LoL players and pros alike. The best Talon rune paths on the position 
Jungle are 
Domination as the primary path and 
Inspiration as the secondary path with a pick rate of 70%. Besides picking runes on Talon you should learn how to play Talon and if you are interested in pro matches take a look on how a pro builds Talon. If you want to discuss 
Talon then you should visit the champion subreddit.
Talon runes from primary path
Domination improves burst damage and assassination tools on Talon. Most of high elo players – and our LoL pros in the the major regions – have agreed that Electrocute is the best keystone rune to run on Talon. This keystone rune provides burst damage, aiding them in nuking down the enemy carries. Other primary runes on Talon are Sudden Impact, Eyeball Collection and Treasure Hunter.
Sudden Impact increases your damage after dashing or being invisible. This is due to how easy it is to activate on Talon with the amount of ways he has to dash, jump or going invisible. The additional lethality helps to take down the priority targets that much easier. Eyeball Collection is next up. This grants the user additional damage with every killing they score. Treasure Hunter is the final rune of the Domination path. This rune gives Talon additional gold for takedowns. The additional gold is nothing to scoff at and can mean the difference between winning or losing a battle. Talon will gain an additional 70 gold for the first takedown. Talon acquires Bounty Hunter Stacks, which Talon may use to get more takedowns. This rune's power will grow tremendously, and Talon will become wealthy like never been before. Each time a fresh stack of Bounty Hunter Stacks is consumed, Talon will get an additional twenty gold.
Talon runes from secondary path
When it comes to your secondary path, most Talon players prefer to go with Inspiration. Inspiration opens creative opportunities on Talon troughout the match. On the Inspiration path, the best runes for Talon are 
Magical Footwear and 
Cosmic Insight.
Magical Footwear allows Talon to focus on those essential core items without the need to spend the additional 300 gold on boots. Cosmic Insight grants summoner spell and item haste.
FAQ for Talon Runes
Which is the best keystone rune on Talon?
The best keystone rune on Talon is Electrocute. This Talon runes setup is then referred as Talon Electrocute.
What runes does Talon use?
Runes from the paths Domination and Inspiration are the most used runes on Talon. For the exact pick rates of Talon runes used, you have to study the rune distribution presented.