Sona Runes explained
There's one set of runes for Sona on patch 14.22 that is the clear favorite for LoL players and pros alike. The best Sona rune paths on the position 
Support are 
Sorcery as the primary path and 
Precision as the secondary path with a pick rate of 72%. Besides picking runes on Sona you should learn how to play Sona and if you are interested in pro matches take a look on how a pro builds Sona. If you want to discuss 
Sona then you should visit the champion subreddit.
Sona runes from primary path
Sorcery empoweres abilities of Sona and increases the available champion resources. Most of high elo players – and our LoL pros in the the major regions – have agreed that 
Summon Aery is the best keystone rune to run on Sona. This keystone rune adds more poke damage to your abilities. And additionally grants an extra shield, whenever Sona empowers or protects an ally with abilities. Other primary runes on Sona are 
Manaflow Band, 
Transcendence and 
Gathering Storm.
This is usually followed up by taking Manaflow Band for additional mana and mana regenaration. Transcendence for some more Ability Haste. Gathering Storm increases your late game power.
Sona runes from secondary path
When it comes to your secondary path, most Sona players prefer to go with Precision. Precision improves attack and sustained damage on Sona troughout the match. On the Precision path, the best runes for Sona are 
Presence of Mind and 
Cut Down.
Presence of Mind helps Sona with the mana problems by restoring missing mana, if a champion is killed. If the enemy team consists of multiple tanks, then the rune Cut Down is the best choice.
FAQ for Sona Runes
Which is the best keystone rune on Sona?
The best keystone rune on Sona is Summon Aery. This Sona runes setup is then referred as Sona Summon Aery.
What runes does Sona use?
Runes from the paths Sorcery and Precision are the most used runes on Sona. For the exact pick rates of Sona runes used, you have to study the rune distribution presented.