Sivir Runes explained
There's one set of runes for Sivir on patch 14.22 that is the clear favorite for LoL players and pros alike. The best Sivir rune paths on the position 
Adc are 
Precision as the primary path and 
Inspiration as the secondary path with a pick rate of 60%. Besides picking runes on Sivir you should learn how to play Sivir and if you are interested in pro matches take a look on how a pro builds Sivir. If you want to discuss 
Sivir then you should visit the champion subreddit.
Sivir runes from primary path
Precision improves attack and sustained damage on Sivir troughout the match. Most of high elo players – and our LoL pros in the the major regions – have agreed that 
Lethal Tempo is the best keystone rune to run on Sivir. This keystone rune gives Sivir a great head start in team fights and allows to put out more damage in that time window. Other primary runes on Sivir are 
Presence of Mind, 
Legend: Bloodline and 
Cut Down.
Presence of Mind helps Sivir with the mana problems by restoring missing mana, if a champion is killed. Legend: Bloodline gives life steal, which aids in winning damage trades and fights in the later stages of the match. If the enemy team consists of multiple tanks, then the rune Cut Down is the best choice.
Sivir runes from secondary path
When it comes to your secondary path, most Sivir players prefer to go with Inspiration. Inspiration opens creative opportunities on Sivir troughout the match. On the Inspiration path, the best runes for Sivir are 
Biscuit Delivery and 
Cosmic Insight.
Biscuit Delivery is a great rune for laning as it gives additional health and mana, which can help in more aggressive lanes. Cosmic Insight grants summoner spell and item haste.
FAQ for Sivir Runes
Which is the best keystone rune on Sivir?
The best keystone rune on Sivir is Lethal Tempo. This Sivir runes setup is then referred as Sivir Lethal Tempo.
What runes does Sivir use?
Runes from the paths Precision and Inspiration are the most used runes on Sivir. For the exact pick rates of Sivir runes used, you have to study the rune distribution presented.