Kayle Runes explained
There's one set of runes for Kayle on patch 15.1 that is the clear favorite for LoL players and pros alike. The best Kayle rune paths on the position 
Top are 
Precision as the primary path and 
Resolve as the secondary path with a pick rate of 53%. Besides picking runes on Kayle you should learn how to play Kayle and if you are interested in pro matches take a look on how a pro builds Kayle. If you want to discuss 
Kayle then you should visit the champion subreddit.
Kayle runes from primary path
Precision improves attack and sustained damage on Kayle troughout the match. Most of high elo players – and our LoL pros in the the major regions – have agreed that 
Lethal Tempo is the best keystone rune to run on Kayle. This keystone rune gives Kayle a great head start in team fights and allows to put out more damage in that time window. Other primary runes on Kayle are 
Presence of Mind, 
Legend: Alacrity and 
Cut Down.
Presence of Mind helps Kayle with the mana problems by restoring missing mana, if a champion is killed. Legend: Alacrity grants additional attack speed to Kayle. If the enemy team consists of multiple tanks, then the rune Cut Down is the best choice.
Kayle runes from secondary path
When it comes to your secondary path, most Kayle players prefer to go with Resolve. Resolve empowers the survivability of Kayle and increases the tankiness. On the Resolve path, the best runes for Kayle are Overgrowth and Bone Plating.
Overgrowth increases your maximum amount of health. Bone Plating make Kayle overall tankier, by decreasing the amount of poke damage in the early game.
FAQ for Kayle Runes
Which is the best keystone rune on Kayle?
The best keystone rune on Kayle is Lethal Tempo. This Kayle runes setup is then referred as Kayle Lethal Tempo.
What runes does Kayle use?
Runes from the paths Precision and Resolve are the most used runes on Kayle. For the exact pick rates of Kayle runes used, you have to study the rune distribution presented.