Aatrox Runes explained
There's one set of runes for Aatrox on patch 14.22 that is the clear favorite for LoL players and pros alike. The best Aatrox rune paths on the position 
Top are 
Precision as the primary path and 
Resolve as the secondary path with a pick rate of 74%. Besides picking runes on Aatrox you should learn how to play Aatrox and if you are interested in pro matches take a look on how a pro builds Aatrox. If you want to discuss 
Aatrox then you should visit the champion subreddit.
Aatrox runes from primary path
Precision improves attack and sustained damage on Aatrox troughout the match. Most of high elo players – and our LoL pros in the the major regions – have agreed that Conqueror is the best keystone rune to run on Aatrox. This keystone rune provides additional power in the later stages of a game. As soon as Conqueror is fully charged, Aatrox deals additional damage and gains life steal. Other primary runes on Aatrox are Triumph, Legend: Alacrity and Last Stand.
Triumph restores on Aatrox a part of missing health and award bonus gold, if a champion is killed. Legend: Alacrity grants additional attack speed to Aatrox. With Last Stand you deal more damage while you are at low health.
Aatrox runes from secondary path
When it comes to your secondary path, most Aatrox players prefer to go with Resolve. Resolve empowers the survivability of Aatrox and increases the tankiness. On the Resolve path, the best runes for Aatrox are 
Overgrowth and 
Second Wind.
Overgrowth increases your maximum amount of health. Second Wind powers up your sustainablity in lane by healing after taking damage from an enemy champion.
FAQ for Aatrox Runes
Which is the best keystone rune on Aatrox?
The best keystone rune on Aatrox is Conqueror. This Aatrox runes setup is then referred as Aatrox Conqueror.
What runes does Aatrox use?
Runes from the paths Precision and Resolve are the most used runes on Aatrox. For the exact pick rates of Aatrox runes used, you have to study the rune distribution presented.