Talon Runes explained
There's one set of runes for Talon on patch 14.9 that is the clear favorite for LoL players and pros alike. The best Talon rune paths on the position 
Jungle are 
Inspiration as the primary path and 
Domination as the secondary path with a pick rate of 91%. Besides picking runes on Talon you should learn how to play Talon and if you are interested in pro matches take a look on how a pro builds Talon. If you want to discuss 
Talon then you should visit the champion subreddit.
Talon runes from primary path
Inspiration opens creative opportunities on Talon troughout the match. Most of high elo players – and our LoL pros in the the major regions – have agreed that 
First Strike is the best keystone rune to run on Talon. Other primary runes on Talon are 
Magical Footwear, 
Future's Market and 
Cosmic Insight.
Magical Footwear allows Talon to focus on those essential core items without the need to spend the additional 300 gold on boots. You can enter debt to buy items, which is displayed as negative gold in your inventary. A small lending fee is added onto the amount of gold you owe after leaving the shop. Cosmic Insight grants summoner spell and item haste.
Talon runes from secondary path
When it comes to your secondary path, most Talon players prefer to go with Domination. Domination improves burst damage and assassination tools on Talon. On the Domination path, the best runes for Talon are 
Sudden Impact and 
Ultimate Hunter.
Sudden Impact increases your damage after dashing or being invisible. This is due to how easy it is to activate on Talon with the amount of ways he has to dash, jump or going invisible. The additional lethality helps to take down the priority targets that much easier. Ultimate Hunter scales up Talon ultimate haste on every unique champion takedown.
FAQ for Talon Runes
Which is the best keystone rune on Talon?
The best keystone rune on Talon is First Strike. This Talon runes setup is then referred as Talon First Strike.
What runes does Talon use?
Runes from the paths Inspiration and Domination are the most used runes on Talon. For the exact pick rates of Talon runes used, you have to study the rune distribution presented.