Kai'Sa Runes explained
There's one set of runes for Kai'Sa on patch 14.9 that is the clear favorite for LoL players and pros alike. The best Kai'Sa rune paths on the position Adc are Domination as the primary path and Inspiration as the secondary path with a pick rate of 51%. Besides picking runes on Kai'Sa you should learn how to play Kai'Sa and if you are interested in pro matches take a look on how a pro builds Kai'Sa. If you want to discuss Kai'Sa then you should visit the champion subreddit.
Kai'Sa runes from primary path
Domination improves burst damage and assassination tools on Kai'Sa. Most of high elo players – and our LoL pros in the the major regions – have agreed that Lethal Tempo is the best keystone rune to run on Kai'Sa. This keystone rune gives Kai'Sa a great head start in team fights and allows to put out more damage in that time window. Other primary runes on Kai'Sa are Taste of Blood, Eyeball Collection and Treasure Hunter.
Taste of Blood heals Kai'Sa as soon as you damage an opposing champion. Eyeball Collection is next up. This grants the user additional damage with every killing they score. Treasure Hunter is the final rune of the Domination path. This rune gives Kai'Sa additional gold for takedowns. The additional gold is nothing to scoff at and can mean the difference between winning or losing a battle. Kai'Sa will gain an additional 70 gold for the first takedown. Kai'Sa acquires Bounty Hunter Stacks, which Kai'Sa may use to get more takedowns. This rune's power will grow tremendously, and Kai'Sa will become wealthy like never been before. Each time a fresh stack of Bounty Hunter Stacks is consumed, Kai'Sa will get an additional twenty gold.
Kai'Sa runes from secondary path
When it comes to your secondary path, most Kai'Sa players prefer to go with Inspiration. Inspiration opens creative opportunities on Kai'Sa troughout the match. On the Inspiration path, the best runes for Kaisa are Biscuit Delivery and Magical Footwear.
Biscuit Delivery is a great rune for laning as it gives additional health and mana, which can help in more aggressive lanes. Magical Footwear allows Kai'Sa to focus on those essential core items without the need to spend the additional 300 gold on boots.
FAQ for Kai'Sa Runes
Which is the best keystone rune on Kai'Sa?
The best keystone rune on Kai'Sa is Lethal Tempo. This Kai'Sa runes setup is then referred as Kai'Sa Lethal Tempo.
What runes does Kai'Sa use?
Runes from the paths Domination and Inspiration are the most used runes on Kai'Sa. For the exact pick rates of Kai'Sa runes used, you have to study the rune distribution presented.