Tristana Runes explained
There's one set of runes for Tristana on patch 13.24 that is the clear favorite for LoL players and pros alike. The best Tristana rune paths on the position 
Adc are 
Precision as the primary path and 
Resolve as the secondary path with a pick rate of 48%. Besides picking runes on Tristana you should learn how to play Tristana and if you are interested in pro matches take a look on how a pro builds Tristana. If you want to discuss 
Tristana then you should visit the champion subreddit.
Tristana runes from primary path
Precision improves attack and sustained damage on Tristana troughout the match. Most of high elo players – and our LoL pros in the the major regions – have agreed that 
Lethal Tempo is the best keystone rune to run on Tristana. This keystone rune gives Tristana a great head start in team fights and allows to put out more damage in that time window. Other primary runes on Tristana are 
Triumph, 
Legend: Alacrity and 
Coup de Grace.
Triumph restores on Tristana a part of missing health and award bonus gold, if a champion is killed. Legend: Alacrity grants additional attack speed to Tristana. Tristana deals with Coup de Grace more damage to targets with low health.
Tristana runes from secondary path
When it comes to your secondary path, most Tristana players prefer to go with Resolve. Resolve empowers the survivability of Tristana and increases the tankiness. On the Resolve path, the best runes for Tristana are 
Bone Plating and 
Demolish.
Bone Plating make Tristana overall tankier, by decreasing the amount of poke damage in the early game. Demolish increases your pressure on the enemy turrets. This rune will help you to punish bad roams or backtimings of your lane opponent.
FAQ for Tristana Runes
Which is the best keystone rune on Tristana?
The best keystone rune on Tristana is Lethal Tempo. This Tristana runes setup is then referred as Tristana Lethal Tempo.
What runes does Tristana use?
Runes from the paths Precision and Resolve are the most used runes on Tristana. For the exact pick rates of Tristana runes used, you have to study the rune distribution presented.